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Study reveals genetic driver for rare metaplastic breast cancer stat : news-medical

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daily : 2017-01-06 & on time : 18:3

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Houston Methodist researchers advance potential treatment for metaplastic breast cancer

Houston Methodist researchers advance potential treatment for metaplastic breast cancer

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Houston Methodist Hospital researchers have advanced a potential treatment for metaplastic breast cancer–the most aggressive subtype of triple negative breast cancer, into patients in just under four years.In a study published in the Journal of the National Cancer Institute (early online Dec. 31), a multi-institutional team led by Jenny C. Chang, M.D., director of the Houston Methodist Cancer Center, identified a gene driving the formation of metaplastic breast cancer.”We not only uncovered the biological pathway stimulating cancer growth, but we found a compound that blocked it, increasing the survival of mice carrying human metaplastic breast tumors,” said Chang, the study’s senior author.

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Grilled meat consumption increases mortality risk among breast cancer survivors

Grilled meat consumption increases mortality risk among breast cancer survivors

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WASHINGTON: Higher consumption of grilled, barbecued and smoked meat may increase the mortality risk among breast cancer survivors, a new study has warned.Researchers, including those from University of North Carolina in the US, evaluated the link between grilled or barbecued and smoked meats and the survival time after breast cancer.High-temperature cooked meat intake is a highly prevalent source of polycyclic aromatic hydrocarbons and other carcinogenic chemicals and has been associated with breast cancer incidence, but this study assessed whether intake is related to survival after breast cancer.

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Grilled, barbecued meats may raise death risk for breast cancer survivors

Grilled, barbecued meats may raise death risk for breast cancer survivors

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Previous studies have linked a high consumption of grilled, barbecued, or smoked meats with an increased risk of breast cancer.Now, a new study finds that it may also increase the risk of all-cause mortality for women who have survived the disease.Cooking meats at high temperatures through barbecuing or grilling leads to the production of chemicals that can increase cancer risk.

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Study reveals genetic driver for rare metaplastic breast cancer

Study reveals genetic driver for rare metaplastic breast cancer

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ANN ARBOR, Mich., Jan. 6 (UPI) — Researchers from the University of Michigan Comprehensive Cancer Center have found a key genetic driver for a rare form of breast cancer.Dr. Celina Kleer, Harold A. Oberman Collegiate Professor of Pathology and director of the Breast Pathology Program at the University of Michigan Comprehensive Cancer Center, has been studying how the CCN6 protein affects breast cancer development for more than a decade.Kleer and her team examined the effects of the deletion of CCN6 from the mammary glands in mice.

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