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Researchers reveal how cancer cells cope with genetic chaos stat : cancerresearchuk

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Researchers reveal how cancer cells cope with genetic chaos

Researchers reveal how cancer cells cope with genetic chaos

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Scientists have uncovered how tumours are able to grow despite significant damage to the structure and number of their chromosomes* – the storage units of DNA – according to two new studies published in Cancer Cell and Cancer Discovery today.”We hope that understanding these mechanisms will allow us to limit drug resistance and improve the efficacy of cancer therapies.” – Professor Charles SwantonHealthy cells are programmed to self-destruct if there are mistakes in their genes that can’t be fixed, but cancer cells can carry on growing with these abnormalities.Over time, further genetic changes allow them to keep growing, spread, and become resistant to treatment.

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Why high-dose vitamin C kills cancer cells: Low levels of catalase enzyme make cancer cells vulnerable to high-dose vitamin C — ScienceDaily

Why high-dose vitamin C kills cancer cells: Low levels of catalase enzyme make cancer cells vulnerable to high-dose vitamin C -- ScienceDaily

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Vitamin C has a patchy history as a cancer therapy, but researchers at the University of Iowa believe that is because it has often been used in a way that guarantees failure.Most vitamin C therapies involve taking the substance orally.However, the UI scientists have shown that giving vitamin C intravenously — and bypassing normal gut metabolism and excretion pathways — creates blood levels that are 100 — 500 times higher than levels seen with oral ingestion.

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Study sheds light on how high-dose vitamin C kills cancer cells

Study sheds light on how high-dose vitamin C kills cancer cells

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IOWA CITY, Iowa, Jan. 9 (UPI) — Researchers at the University of Iowa have determined that the delivery method plays a vital role in how high-dose vitamin C kills cancer cells.Standard vitamin C therapies involve the patient taking the vitamin orally.However, researchers have found that when vitamin C is given intravenously, blood levels are 100 to 500 times higher than levels seen with oral ingestion.

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