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Roots of Alzheimer’s disease can extend as far back as the womb quoting : medical xpress

according to “In some cases, providing supplements to the newborn Alzheimer’s Disease model mice could reduce the amyloid beta level and improve learning and memory deficits,” said Song.
The researchers found that even a mild vitamin A deficiency increased the production of amyloid beta, the protein that forms plaques that smother and ultimately kill neurons in Alzheimer’s disease.
“Our study clearly shows that marginal deficiency of vitamin A, even as early as in pregnancy, has a detrimental effect on brain development and has long-lasting effect that may facilitate Alzheimer’s Disease in later life,” said Dr. Weihong Song, a professor of psychiatry and Canada Research Chair in Alzheimer’s Disease.
Explore further: Certain factors affect vitamin D levels in children with chronic kidney disease
For this research, Song built on previous studies that have linked low levels of vitamin A with cognitive impairments.

Roots of Alzheimer's disease can extend as far back as the womb

referring to Advancing the fight against Alzheimer’s disease, Japanese researchers have in a breakthrough study, developed a new drug that could help treat the most common form of dementia.
A dysfunction in the acetylcholine system is believed to be one of the causes of Alzheimer’s disease (AD) and vascular dementia.
Alzheimer’s is a progressive disease that destroys memory and other important mental functions.
The drug SAK3 is now in the preclinical stage of drug development and clinical trials are expected to begin in the next few years, the researchers said.
SAK3 also halted the production of amyloid beta protein — the main component of the amyloid plaques found in the brains of Alzheimer patients.

referring to

Alzheimer’s disease may begin in the womb

Not eating enough fruits and vegetables while you’re pregnant could lead to Alzheimer’s disease in your children, a new study claims.
Dr Song said: ‘In some cases, providing supplements to the newborn Alzheimer’s disease mice could reduce the amyloid beta level and improve learning and memory deficits.
But the groundbreaking study also found the onset of the degenerative brain disease could be slowed by supplementing babies’ diets with the vital nutrient.
Mice who were deprived in the womb did better in the tests when given supplements than those who were not fed them.
Mice that did not get enough vitamin A in the womb and during infancy performed worse as adults on a standard test of learning and memory.

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