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sciencedaily : declared in Report describes VHA clinical demonstration project for lung cancer screening — ScienceDaily

according to The VHA implemented a three-year lung cancer demonstration project in eight geographically diverse hospitals to understand the feasibility and implications for patients and clinical staff of a lung cancer screening program.
Implementing a comprehensive lung cancer screening program was challenging and complex according to a new article published online by JAMA Internal Medicine that describes a lung cancer demonstration project conducted at eight academic Veterans Health Administration hospitals.
The U.S. Preventive Services Task Force recommends annual lung cancer screening with low-dose computed tomography for current and heavy smokers who are ages 55 to 80.
“The VHA LCSDP [lung cancer screening demonstration project] found implementing a comprehensive LCS [lung cancer screening] program that followed recommendations to be challenging and complex, requiring new tools and patient care processes for staff as well as dedicated patient coordination,” the authors note.
Ultimately, 2,106 patients had lung cancer screening between July 2013 and June 2015.

referring to

Scancell taps lung cancer nonprofit to accelerate trial recruitment

U.K. biotech Scancell is taking no chances when it comes to carrying out trials of its candidate vaccine for non-small cell Lung Cancer (NSCLC).
The phase 1/2 trial is due to get underway next year.
Last October, Scancell said it was assembling an investigation team to assist in finalising the NSCLC trial design.
The company has joined forces with the Addario Lung Cancer Medical Institute (ALCMI) and Bonnie J. Addario Lung Cancer Foundation (ALCF) to make sure that its planned phase 1/2 trial of immunotherapy SCIB2—due to start next year—recruits patients as quickly as possible.
The new batch is being used for a long-term extension position of the phase 1/2 study and also for a new trial testing SCB1 in tandem with checkpoint inhibitors.
These cells may explain why smoking causes lung cancer

referring to She points out that smoking also causes other lung cancers that don’t arise from basal stem cells.
“It isn’t definitive but the evidence is that lung basal stem cells are the likely cells of origin.”The unmasking of basal stem cells, published in the Public Library of Science: Biology, provides a crucial new target for developing drugs that may be able to turn off the progress of the cancer.
It was clear evidence that basal stem cells are the likely culprits in how the cancer is triggered.
She would then have to get the stem cells to grow into colonies to prove they were indeed stem cells and that her isolation process was working.
When we breathe in something like cigarette smoke that causes lung damage, these basal cells receive a signal to grow and repair the damage.

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