as informed in The scientists also show that their rat model can give insight into the phenomenon of weight regain after weight loss.
Formerly, different strains of rats were used in obesity research: a strain that was known for its leanness, and a strain known to become obese.
In other words, keeping a reduced weight for a longer time makes one regain weight quicker once one starts to relapse to old and even higher weight, in males.
Giles research team collected data of more than 300 animals to find the optimal time point to identify early in life an animal’s predisposition to become obese.
The work discusses how the common neglect of sex differences can make the prediction and treatment of long-term obesity in females very difficult.
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Low social rank bigger health risk than obesity
This makes social rank a bigger risk factor for illness and premature death than either high alcohol consumption or obesity, and it nearly equals the risk posed by physical inactivity, researchers said.
Social rank could be improved by government policies on tax or education, for example, said the study, published in The Lancet.
The study was the first attempt to weigh the health risk of socioeconomic status against other “modifiable” factors, the authors said, at least in high-income countries.
On average, a low social rank shaved over 25 months off the average lifespan, compared with six months for heavy alcohol intake and eight months for obesity, according to Lifepath, a European Commission-funded consortium that conducted the study.
“Low socioeconomic status is one of the strongest predictors of premature mortality worldwide, but health policymakers often do not consider it a risk factor to target,” Lifepath said in a statement.
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Poverty harms health more than obesity or alcohol
Being poor is a bigger health risk than being fat or having high blood pressure, a major study has concluded.
The study is the first to compare the impact of low socioeconomic status on health with other major risk factors.
Politicians are being urged to take low socioeconomic status into account when forming health policies after a study of 1.7 million people found that it was a big risk factor for ill health and early death.
Poorer people’s life expectancy was reduced by 2.1 years, greater than the reductions associated with high blood pressure, obesity and high alcohol consumption, of 1.6, 0.7 and 0.5 years respectively.
Being inactive reduced life expectancy by 2.4 years, and smoking and diabetes by 4.8 and 3.9 years.
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