according to With opioid prescribing, “there isn’t a really unified principal around the way we do things.
In addition, patients who received a large dose of opioids at their initial visit were more likely to end up as long-term users.
One question raised by the study is why other doctors offering follow-up care after an ER visit would continue to prescribe opioids for so long.
But the large sample size and the clear results allowed the researchers to confidently conclude that the initial prescriber’s decision is associated with the likelihood of long-term use.
Long-term use, in this context, does not mean addiction or physical dependence on the drug.
as informed in
Potent compound in snail venom could be painkiller to end opioid epidemic
A compound extracted from the venom of a small marine snail may act as a potent painkiller, scientists have found.
They synthetically engineered 20 analogs of the natural compound RgIA to test how they interacted with the receptor.
They studied the little cone marine snail known as Conus regius, whose powerful venom is capable of paralysing and killing its preys.
It could provide a solution to the current opioid epidemic that is currently devastating the US.
“We found that the compound was still working 72 hours after the injection, still preventing pain,” McIntosh added in a statement.
as informed in Feb. 20 (UPI) — A novel compound produced by a tiny marine snail species could inspire an alternative to opioids, the highly addictive class of pain killers.
Researchers published their tests results in the journal Proceedings of the National Academy of Sciences.
Olivera and his colleagues isolated the main compound, Rg1A, from the snail’s venom and tested its pain-reduction abilities on rodents.
The predatory “crown cone” sea snail, Conus regius, uses venom to paralyze and kill its prey.
“Nature has evolved molecules that are extremely sophisticated and can have unexpected applications,” Baldomera Olivera, a professor of biology at the University of Utah, explained in a news release.
This content may collect you by Michael Daniel